Skip to main content
. 2020 Jun 2;15(1):492–500. doi: 10.1515/med-2020-0047

Figure 2.

Figure 2

The expression of miR-491-5p that directly targets MMP-9 and MMP-9 was upregulated in the atherosclerotic tissues and plasma. (a) The predicted miR-491-5p binding site in the 3′-UTR of MMP-9. (b) The dual-luciferase analysis was used to confirm the binding sites between miR-491-5p and 3′-UTR MMP-9. (c) Expressions of MMP-9 at mRNA level in the plasma samples of the patients with atherosclerosis were detected by qRT-PCR. (d) Expressions of MMP-9 at mRNA level in atherosclerotic plaque tissues were detected by qRT-PCR. The data are expressed as mean ± SD; **p < 0.01 vs. mimic control; ##p < 0.01 vs. healthy control; &&p < 0.01 vs. normal tissue.