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. 2020 Jun 2;15(1):492–500. doi: 10.1515/med-2020-0047

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© 2020 Zhonghan He et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

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Downregulation of miR-491-5p enhanced hVSMC viability and migration and reduced the apoptosis. The hVSMCs were pretreated with inhibitor control or miR-491-5p inhibitor for 48 h. (a) The effect of miR-491-5p inhibitor on hVSMC viability was monitored by the MTT assay. (b) The effect of miR-491-5p inhibitor on hVSMC migration was determined by the transwell assay. (c and d) Apoptosis of hVSMCs was evaluated by the flow cytometric analysis. Data are shown as mean ± SD. *, **p < 0.05, 0.01 vs. control.