Table 1.
Clinical and biochemical characteristics of participants
| Variables | Diabetic control (n = 40) | DFU (n = 28) | P value |
|---|---|---|---|
| Age (year) | 63.55 ± 2.22 | 65.32 ± 2.65 | 0.6101 |
| Sex (Female,%) | 16 (40.0%) | 13 (46.4%) | 0.5981 |
| Drinking(n,%) | 6 (15.0%) | 4 (14.3%) | 0.0008* |
| Diabetes duration (year) | 11.99 ± 1.47 | 14.43 ± 1.79 | 0.2957 |
| SBP (mmHg) | 126.4 ± 3.53 | 134.46 ± 4.22 | 0.1483 |
| DBP (mmHg) | 75.20 ± 1.86 | 75.57 ± 2.22 | 0.8985 |
| FBG (mmol/L) | 9.69 ± 0.65 | 8.59 ± 0.78 | 0.6259 |
| HbA1c(%) | 9.86 ± 0.39 | 9.13 ± 0.45 | 0.2236 |
| TC (mmol/L) | 3.98 ± 0.20 | 4.02 ± 0.24 | 0.8846 |
| TG (mmol/L) | 1.72 ± 0.16 | 1.45 ± 0.20 | 0.2913 |
| HDL-c (mmol/L) | 0.97 ± 0.04 | 0.90 ± 0.04 | 0.2208 |
| LDL-c (mmol/L) | 2.46 ± 0.15 | 2.59 ± 0.18 | 0.5831 |
| ALT(U/L) | 20.23 ± 3.75 | 23.60 ± 4.43 | 0.5625 |
| AST(U/L) | 16.38 ± 3.17 | 24.11 ± 3.73 | 0.1197 |
| γ-GT(U/L) | 25.13 ± 6.54 | 38.48 ± 7.86 | 0.1965 |
| WBC(109/L) | 7.67 ± 0.68 | 10.15 ± 0.81 | 0.0220* |
| Neutrophil(%) | 65.10 ± 2.12 | 70.92 ± 2.53 | 0.0828 |
| Monocytes(%) | 9.38 ± 1.75 | 14.27 ± 2.09 | 0.7780 |
| Lymphocyte(%) | 22.01 ± 1.46 | 12.57 ± 1.74 | 0.0001* |
| CRP (ng/mL) | 13.95 ± 9.56 | 56.12 ± 10.93 | 0.0052* |
| ESR (mm/h) | 15.56 ± 4.81 | 71.78 ± 5.56 | < 0.0001* |
| Hypertension(n,%) | 28 (70.0%) | 17 (60.7%) | 0.4270 |
| Coronary heart disease(n,%) | 10 (25.0%) | 8 (28.6%) | 0.7431 |
| Cerebral vascular disease(n,%) | 13 (32.5%) | 8 (28.6%) | 0.7294 |
| Diabetic retinopathy(n,%) | 20 (50.0%) | 10 (35.7%) | 0.2429 |
| Diabetic nephropathy(n,%) | 15 (37.5%) | 7 (25.0%) | 0.2782 |
| Amputation(n,%) | 0 (0.0%) | 10 (35.7%) | – |
SBP Systolic blood pressure, DBP Diastolic blood pressure, FBG Fasting plasma glucose, HbA1c Glycated hemoglobin A1c, TC Total cholesterol, TG Triglyceride, HDL-c HDL cholesterol, LDL-c LDL cholesterol, ALT Alanine aminotransferase, AST Aspartate aminotransferase, γ-GT γ-glutamyl transpeptidase, WBC White blood cell, CRP C-reactive protein, ESR Erythrocyte sedimentation rate. * indicates the difference between groups reaching significance