Table 3.
Clinical initial staging and surgery in patients who developed systemic or local relapse
| Group | Distance from AV | T | N | CMR | EMVI | LPLN | Induction | Adjuvant | Relapse | Rescue |
|---|---|---|---|---|---|---|---|---|---|---|
| CT | CT | Surgery | ||||||||
| 1cCR | 3 | 3 | 0 | Free | No | No | No | No | Local | APR |
| 1cCR | 3 | 3 | 1 | Free | No | No | No | Yes | Local | APR |
| 1cCR | 2 | 4b | 0 | Involved | No | No | No | No | Systemic | – |
| 2pCR | 2 | 4b | 0 | Involved | No | No | No | No | Local | No |
| 2pCR | 10 | 3b | 1 | Free | Present | Present | No | Yes | Systemic | – |
| 2pCR | 3 | 3c | 2a | Free | No | No | No | Yes | Systemic | – |
| 2pCR | 3 | 4b | 0 | Involved | No | No | Recived | no | Systemic | – |
cCR clinical complete response, pCR pathological complete response, AV anal verge, CRM circumferential resection margin, EMVI extramural vascular invasion, LPLN lateral pelvic lymph nodes, CT chemotherapy, APR abdominoperineal resection