Table 3.
Blood Chemistry Analysis of Male and Female Wild-Type (WT) and Cd82−/− (KO) Mice
| Male |
Female |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normal range |
Normal range |
WT M vs. F (P-value) | KO M vs. F (P-value) | WT vs. KO M & F (P-value) | ||||||||||
| Assay | Units | WTO | KO | Low | High | P-value | WT | KO | Low | High | P-value | |||
| ALB | g/dl | 3.4 | 3.5 | 2.1 | 2.46 | 0.572 | 4.1 | 3.6 | 2.72 | 2.32 | 0.082 | 0.013 | 0.151 | 0.836 |
| ALP | U/L | 82 | 83 | 125 | 176 | 0.943 | 155 | 129 | 153 | 210 | 0.276 | 0.037 | 0.022 | 0.880 |
| ALT | U/L | 57 | 51 | 45 | 93 | 0.430 | 37.3 | 40.6 | 41 | 76 | 0.728 | 0.091 | 0.166 | 0.383 |
| AMY | U/L | 1,034 | 1,050 | 0.818 | 1,116 | 974 | 0.495 | 0.679 | 0.472 | 0.609 | ||||
| TBIL | mg/dl | 0.3 | 0.3 | 0.1 | 0.29 | 1.000 | 0.3 | 0.3 | 0.1 | 0.32 | 0.688 | 0.511 | 0.710 | 0.925 |
| BUN | mg/dl | 23.5 | 21.6 | 17.5 | 23.2 | 0.067 | 23.0 | 19.4 | 13.7 | 20.4 | 0.251 | 0.575 | 0.106 | 0.027 |
| Ca++ | mg/dl | 9.9 | 9.8 | 9.85 | 10.54 | 0.743 | 10.0 | 9.8 | 9.94 | 10.55 | 0.560 | 0.444 | 0.985 | 0.531 |
| PHOS | mg/dl | 8.3 | 8.3 | 10 | 12.37 | 0.935 | 8.7 | 8.3 | 8.51 | 12.23 | 0.714 | 0.524 | 0.973 | 0.779 |
| CRE | mg/dl | 0.4 | 0.2 | 0.24 | 0.32 | 0.020 | 0.3 | 0.4 | 0.22 | 0.31 | 0.049 | 0.604 | 0.003 | 0.634 |
| GLU | mg/dl | 148 | 146 | 139.3 | 184.3 | 0.911 | 152 | 132 | 139.2 | 194.1 | 0.465 | 0.859 | 0.519 | 0.520 |
| Na+ | mmol/L | 159 | 157 | 149.4 | 153.4 | 0.247 | 162 | 154 | 147.7 | 151.2 | 0.025 | 0.125 | 0.002 | 0.010 |
| K+ | mmol/L | 6.6 | 6.7 | 5.54 | 7 | 0.490 | 6.8 | 6.2 | 5.78 | 6.61 | 0.173 | 0.802 | 0.014 | 0.410 |
| TP | g/dl | 6.0 | 6.1 | 4.92 | 5.5 | 0.688 | 6.4 | 6.1 | 5.1 | 5.57 | 0.241 | 0.171 | 0.890 | 0.678 |
| GLOB | g/dl | 2.7 | 2.6 | 0.802 | 2.3 | 2.4 | 0.581 | 0.058 | 0.081 | 0.736 | ||||
| CLORIDE | mmol/L | 116 | 112 | 110.8 | 116.9 | 0.149 | 117 | 114 | 112.1 | 116.3 | 0.532 | 0.286 | 0.611 | 0.103 |
| LIPASE | U/L | 904 | 948 | 0.301 | 1,385 | 1,145 | 0.143 | 0.003 | 0.004 | 0.974 | ||||
| CHOL. | mg/dl | 106 | 103 | 100 | 116 | 0.673 | 106 | 87 | 88 | 110 | 0.340 | 0.865 | 0.124 | 0.214 |
| TRIGLY | mg/dl | 130 | 128 | 0.884 | 80 | 109 | 0.137 | 0.009 | 0.171 | 0.752 | ||||
| AST | U/L | 107 | 101 | 65 | 142 | 0.738 | 73 | 102 | 57 | 199 | 0.387 | 0.221 | 0.941 | 0.884 |
| IRON | mg/dl | 148 | 167 | 145.1 | 215.7 | 0.286 | 156 | 164 | 146.2 | 223.3 | 0.693 | 0.686 | 0.890 | 0.230 |
ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AMY, amylase; TBIL, total bilirubin; BUN, blood urea nitrogen; PHOS, phosphorus; CRE, creatinine; GLU, glucose; TP, total protein; GLOB, globulin; CHOL., cholesterol; TRYGLY, tryglycerides; AST, aspartate aminotransferase.
Values of pooled samples from eight mice each of male WT, KO and female KO and of four female WT mice.
P-values < 0.05 are indicated in bold face.