Table 4.
Blood Composition (CBC) Analysis of Male and Female Wild-Type (WT) and Cd82−/− (KO) Mice
| Male |
Female |
Normal range |
WT M vs. F (P-value) | KO M vs. F (P-value) | WT vs. KO M & F (P-value) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Assay | WT | KO | P-value | WT | KO | P-value | Low | High | |||
| Leukocytes | |||||||||||
| WBC | 9.00 | 8.47 | 0.506 | 5.48 | 5.74 | 0.755 | 1.8 | 10.7 | 0.003 | 0.0004 | 0.141 |
| NE | 2.46 | 2.49 | 0.931 | 1.07 | 1.48 | 0.123 | 0.1 | 2.4 | 0.001 | 0.004 | 0.646 |
| LY | 6.21 | 5.60 | 0.261 | 4.20 | 4.02 | 0.802 | 0.9 | 9.3 | 0.019 | 0.003 | 0.059 |
| MO | 0.274 | 0.309 | 0.471 | 0.175 | 0.218 | 0.376 | 0 | 0.4 | 0.037 | 0.074 | 0.704 |
| EO | 0.044 | 0.054 | 0.567 | 0.027 | 0.031 | 0.748 | 0 | 0.2 | 0.335 | 0.186 | 0.810 |
| BA | 0.008 | 0.014 | 0.260 | 0.003 | 0.008 | 0.326 | 0 | 0.2 | 0.193 | 0.353 | 0.234 |
| Leukocytes (%) | |||||||||||
| NE | 27.43 | 28.58 | 0.708 | 20.69 | 26.60 | 0.150 | 6.6 | 38.9 | 0.055 | 0.557 | 0.415 |
| LY | 68.84 | 67.19 | 0.619 | 75.31 | 68.53 | 0.163 | 55.8 | 91.6 | 0.103 | 0.723 | 0.308 |
| MO | 3.13 | 3.51 | 0.362 | 3.28 | 4.03 | 0.418 | 0 | 7.5 | 0.789 | 0.411 | 0.143 |
| EO | 0.50 | 0.57 | 0.746 | 0.62 | 0.65 | 0.927 | 0 | 3.9 | 0.642 | 0.738 | 0.653 |
| BA | 0.09 | 0.15 | 0.290 | 0.11 | 0.19 | 0.524 | 0 | 2 | 0.835 | 0.684 | 0.196 |
| Erythrocytes | |||||||||||
| RBC | 10.11 | 10.48 | 0.148 | 9.83 | 9.94 | 0.712 | 6.36 | 9.42 | 0.377 | 0.039 | 0.412 |
| Hb | 14.33 | 14.55 | 0.571 | 14.30 | 14.43 | 0.736 | 11 | 15.1 | 0.961 | 0.720 | 0.530 |
| HCT | 41.68 | 42.74 | 0.535 | 42.17 | 41.71 | 0.796 | 35.1 | 45.4 | 0.815 | 0.507 | 0.746 |
| MCV | 41.14 | 40.69 | 0.603 | 42.87 | 41.94 | 0.269 | 45.4 | 60.3 | 0.108 | 0.105 | 0.678 |
| MCH | 14.16 | 13.89 | 0.085 | 14.55 | 14.54 | 0.961 | 14.1 | 19.3 | 0.126 | 0.0004 | 0.818 |
| MCHC | 34.48 | 34.22 | 0.657 | 34.02 | 34.71 | 0.310 | 30.2 | 34.2 | 0.489 | 0.410 | 0.765 |
| RDW | 18.30 | 18.36 | 0.803 | 18.10 | 17.88 | 0.511 | 12.4 | 27 | 0.595 | 0.046 | 0.481 |
| Thrombocytes | |||||||||||
| PLT | 980 | 969 | 0.840 | 771 | 879 | 0.148 | 592 | 2,972 | 0.008 | 0.140 | 0.961 |
| MPV | 4.17 | 4.24 | 0.635 | 4.17 | 4.26 | 0.615 | 5 | 20 | 0.991 | 0.852 | 0.444 |
WBC, white blood cells; NE, neutrophils; LY, lymphocytes; MO, monocytes; EO, eosinophils; BA, basophils; RBC, red blood cells; Hb, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; PLT, platelets; MPV, mean platelet volume.
Average values of eight mice each of male WT, KO and female KO and of four female WT mice.
P-values < 0.05 are indicated in bold face.