Table 5.
Differentially Expressed Genes Up- and Down-Regulated by Kai1/Cd82−/− in Male MEFs
| Affymetrix Id | Gene | Description | M KO signal | M WT signal | F KO signal | F WT signal | Male KO/WT | P-value | Female KO/WT | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
| Male | ||||||||||
| 1421058_at | Adh7 | Alcohol dehydrogenase 7, mu or sigma | 11 | 184 | 13 | 22 | 0.0609 | 6E–06 | 0.5882 | 0.2169 |
| 1460248_at | Cpxm2 | Carboxypeptidase X 2 (M14 family) | 51 | 488 | 39 | 39 | 0.1045 | 5E–10 | 1.0055 | 0.9806 |
| 1419728_at | Cxcl5 | Chemokine (C-X-C motif) ligand 5 | 7 | 231 | 5 | 5 | 0.0302 | 3E–06 | 1.1236 | 0.8662 |
| 1418283_at | Cldn4 | Claudin 4 | 170 | 20 | 283 | 144 | 8.5366 | 0.0023 | 1.9665 | 0.0001 |
| 1453092_at | Crct1 | Cysteine-rich C-terminal 1 | 1,711 | 196 | 2,332 | 1,247 | 8.7516 | 1E–09 | 1.8697 | 2E–08 |
| 1435494_s_at | Dsp | Desmoplakin | 109 | 16 | 247 | 47 | 6.7231 | 4E–05 | 5.2668 | 8E–06 |
| 1439746_at | Dusp27 | Dual specificity phosphatase 27 (putative) | 233 | 24 | 246 | 184 | 9.6682 | 0.0015 | 1.3407 | 0.021 |
| 1422947_at | Hist1h3a | Histone cluster 1, H3a | 233 | 15 | 314 | 118 | 16.013 | 5E–06 | 2.6684 | 1E–06 |
| 1428014_at | Hist1h4h | Histone cluster 1, H4h | 241 | 27 | 309 | 135 | 8.9152 | 1E–05 | 2.3 | 3E–05 |
| 1449499_at | Hoxa7 | Homeo box A7 | 270 | 16 | 245 | 232 | 16.514 | 2E–09 | 1.0549 | 0.5373 |
| 1457666_s_at | Ifi202b | Interferon-activated gene 202B | 1 | 3,269 | 3 | 1 | 0.0004 | 7E–11 | 2.2985 | 0.1337 |
| 1451567_a_at | Ifi203 | Interferon-activated gene 203 | 82 | 1,184 | 116 | 182 | 0.0689 | 3E–10 | 0.6393 | 0.0131 |
| 1426278_at | Ifi27 | Interferon, alpha-inducible protein 27 | 115 | 1,337 | 191 | 200 | 0.0864 | 2E–08 | 0.9537 | 0.5953 |
| 1427300_at | Lhx8 | LIM homeobox protein 8 | 37 | 514 | 68 | 38 | 0.0729 | 4E–08 | 1.7899 | 0.0573 |
| 1425828_at | Nkx6-1 | NK6 homeobox 1 | 125 | 19 | 157 | 108 | 6.4826 | 1E–05 | 1.4504 | 0.0832 |
| 1434046_at | AA467197 | Dresden Prostate Cancer Associated 2 | 14 | 220 | 22 | 128 | 0.0644 | 2E–06 | 0.1748 | 2E–05 |
| 1457088_at | Pldn | Pallidin | 324 | 35 | 342 | 42 | 9.3682 | 1E–09 | 8.0977 | 7E–09 |
| 1421917_at | Pdgfra | Platelet-derived growth factor receptor, alpha | 121 | 1,293 | 69 | 112 | 0.0936 | 6E–10 | 0.6186 | 0.0164 |
| 1417466_at | Rgs5 | Regulator of G-protein signaling 5 | 882 | 118 | 1,277 | 702 | 7.4665 | 4E–09 | 1.8201 | 0.0007 |
| 1449340_at | Sostdc1 | Sclerostin domain containing 1 | 31 | 334 | 47 | 36 | 0.0919 | 1E–05 | 1.3274 | 0.1462 |
| 1418105_at | Stmn4 | Stathmin-like 4 | 278 | 22 | 344 | 251 | 12.612 | 0.0003 | 1.3722 | 0.0015 |
| 1442140_at | Tnn | Tenascin N | 92 | 1,855 | 46 | 43 | 0.0495 | 2E–10 | 1.0673 | 0.9125 |
| 1424454_at | Tmem87a | Transmembrane protein 87A | 1,041 | 19 | 1,025 | 29 | 54.054 | 4E–06 | 35.777 | 2E–09 |
| 1429947_a_at | Zbp1 | Z-DNA binding protein 1 | 29 | 390 | 81 | 70 | 0.0736 | 7E–05 | 1.163 | 0.5703 |
M, male; F, female; WT, Cd82+/+; KO, Cd82−/−; KO/WT, Cd82−/−/Cd82+/+ signal ratio.
Signal values are geometric mean values.