Table 6.
Differentially Expressed Genes Up- and Down-Regulated by Kai1/Cd82−/− in Female MEFs
| Affymetrix Id | Gene | Description | M KO signal | M WT signal | F KO signal | F WT signal | Male KO/WT | P-value | Female KO/WT | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
| 1458560_at | Aspm | Abnormal spindle-like, microcephaly associated | 85 | 223 | 63 | 150 | 0.3821 | 0.0038 | 0.4178 | 0.0003 |
| 1448595_a_at | Bex1 | Brain expressed gene 1 | 982 | 305 | 3,461 | 850 | 3.2185 | 3E–09 | 4.0696 | 4E–06 |
| 1449434_at | Car3 | Carbonic anhydrase 3 | 61 | 10 | 166 | 37 | 6.0038 | 0.0019 | 4.5467 | 2E–05 |
| 1418710_at | Cd59a | CD59a antigen | 295 | 690 | 390 | 1,305 | 0.4274 | 5E–06 | 0.2987 | 2E–10 |
| 1454112_a_at | Cep27 | centrosomal protein 27 | 121 | 325 | 114 | 303 | 0.3716 | 7E–08 | 0.3765 | 7E–06 |
| 1448734_at | Cp | Ceruloplasmin | 76 | 38 | 347 | 64 | 2.0054 | 0.0348 | 5.3877 | 2E–06 |
| 1424131_at | Col6a3 | Collagen, type VI, alpha 3 | 3,119 | 10,666 | 1,471 | 3,923 | 0.2924 | 1E–07 | 0.3749 | 1E–09 |
| 1435494_s_at | Dsp | Desmoplakin | 109 | 16 | 247 | 47 | 6.7231 | 4E–05 | 5.2668 | 8E–06 |
| 1452406_x_at | Erdr1 | Erythroid differentiation regulator 1 | 411 | 1,191 | 237 | 1,270 | 0.3448 | 0.0432 | 0.1868 | 0.0004 |
| 1445191_at | Exdl1 | Exonuclease 3′–5′ domain-like 1 | 131 | 34 | 176 | 27 | 3.8183 | 3E–05 | 6.5177 | 0.0004 |
| 1456655_at | Ext1 | Exostosin-1 | 1,510 | 2,182 | 59 | 1190 | 0.6917 | 0.0552 | 0.0495 | 3E–08 |
| 1416200_at | Il33 | Interleukin 33 | 130 | 45 | 363 | 83 | 2.9143 | 0.0002 | 4.3525 | 3E–06 |
| 1425045_at | Jmjd7 | jmjC domain-containing protein 7 | 62 | 206 | 79 | 252 | 0.3013 | 1E–07 | 0.3119 | 1E–06 |
| 1417595_at | Meox1 | Mesenchyme homeobox 1 | 92 | 366 | 56 | 143 | 0.2522 | 0.0001 | 0.3911 | 0.0005 |
| 1434046_at | AA467197 | Dresden prostate cancer associated 2 | 14 | 220 | 22 | 128 | 0.0644 | 2E–06 | 0.1748 | 2E–05 |
| 1419271_at | Pax6 | Paired box gene 6 | 34 | 21 | 122 | 26 | 1.5808 | 0.361 | 4.7538 | 0.0002 |
| 1457088_at | Pldn | Pallidin | 324 | 35 | 342 | 42 | 9.3682 | 1E–09 | 8.0977 | 7E–09 |
| 1449586_at | Pkp1 | Plakophilin 1 | 141 | 264 | 77 | 258 | 0.5355 | 0.0015 | 0.2994 | 0.0081 |
| 1434365_a_at | Scyl3 | Protein-associating with the carboxyl-terminal | 93 | 217 | 52 | 142 | 0.4284 | 0.0002 | 0.3639 | 0.0002 |
| 1444061_at | A030004J04Rik | RIKEN cDNA A030004J04 gene | 98 | 45 | 328 | 77 | 2.1624 | 0.0101 | 4.2384 | 4E–07 |
| 1422198_a_at | Shmt1 | Serine hydroxymethyltransferase 1 (soluble) | 59 | 234 | 32 | 101 | 0.2538 | 0.0027 | 0.318 | 0.0029 |
| 1454211_a_at | Shroom3 | Shroom family member 3 | 93 | 30 | 203 | 25 | 3.067 | 0.0224 | 8.2233 | 0.0027 |
| 1424454_at | Tmem87a | Transmembrane protein 87A | 1,041 | 19 | 1,025 | 29 | 54.054 | 4E–06 | 35.777 | 2E–09 |
M, male; F, female; WT, Cd82+/+; KO, Cd82−/−; KO/WT, Cd82−/−/Cd82+/+ signal ratio.
Signal values are geometric mean values.