Table 1.

Accuracy of aortic valve calcium score measured by multidetector computed tomography to predict severe aortic stenosis in patients with normal left ventricular outflow

Aortic valve calcium score measured by CT (n=518)	Men				Women
	AUC	Cutoff	Sensitivity (%)	Specificity (%)	AUC	Cutoff	Sensitivity (%)	Specificity (%)
Valve calcium score	0.93	2067 AU	93	81	0.92	1172 AU	88	87
Valve calcium score/aortic annulus CSA	0.95	510 AU/cm2	92	85	0.93	292 AU/cm2	92	83

Severe AS was defined as an AVA ≤1.0 cm² and a mean gradient ≥40 mmHg. Normal LV outflow was defined as a stroke volume index >35 mL/m² and a mean transvalvular flow rate >210 ml/s. These data were prospectively collected in 3 centers: QHLI, Bichat Hospital, and Mayo Clinic (31–34). ROC=Receiver operating characteristic, AUC=Area under the ROC curve, CSA=Cross-sectional area, SAVR=Surgical aortic valve replacement, LV=Left ventricular, AVA=Aortic valve area, QHLI=Quebec heart and lung institute