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Effect of hesperidin on blood glucose and insulin levels. Rats were treated with alloxan and high fat diet to induce diabetes before blood was sampled to determine (A) blood glucose and (B) insulin levels. (C) Insulin resistance index was assessed using the HOMA-IR = fasting glucose (mmol/l) x fasting insulin (mIU/ml)/22.5. Data are presented as the mean ± SD, n=8. ##P<0.01 vs. naïve group; **P<0.01 vs. model group. HOMA-IR, homeostasis model assessment-insulin resistance.
