Table 1.
PCGs with RNAi phenotypes
| gene | RNAi phenotype | reference(s) |
|---|---|---|
| notum | anterior-facing tail | (Petersen and Reddien, 2011) |
| wntl | posterior-facing head; tailless | (Adell et al., 2009; Petersen and Reddien, 2009) |
| wnt11-2 | medial fusion of posterior anatomy | (Adell et al., 2009; Gurley et al., 2010) |
| wntP-2 / wnt11-5 | posterior-facing head; two pharynges | (Petersen and Reddien, 2009; Sureda-Gómez et al., 2015; Lander and Petersen, 2016; Scimone et al., 2016) |
| wnt11-1 | shorter tail; two pharynges | (Sureda-Gómez et al., 2015) |
| wnt5 | lateral duplication of medial anatomy | (Adell et al., 2009; Gurley et al., 2010; Almuedo-Castillo et al., 2011; Oderberg et al., 2017; Atabay et al., 2018) |
| wntA | posterior expansion of eyes and brain | (Kobayashi et al., 2007; Scimone et al., 2016) |
| frizzled5/8-4 | posterior expansion of eyes and brain | (Scimone et al., 2016) |
| wntless | posterior-facing head | (Adell et al., 2009) (Almuedo-Castillo et al., 2011) |
| teashirt | posterior-facing head | (Owen et al., 2015; Reuter et al., 2015) |
| Djislet | tailless | (Hayashi et al., 2011) |
| prep | failed anterior identity regeneration | (Felix and Aboobaker, 2010) |
| foxD | failed anterior and medial identity regeneration | (Roberts-Galbraith and Newmark, 2013; Scimone et al., 2014; Vogg et al., 2014) |
| zic-1 | failed anterior identity regeneration | (Vasquez-Doorman and Petersen, 2014; Vogg et al., 2014) |
| zic-2 | defective anterior identity regeneration | (Vasquez-Doorman and Petersen, 2014; Vogg et al., 2014) |
| bmp | ventralization | (Molina et al., 2007; Orii and Watanabe, 2007; Reddien et al., 2007) |
| admp | ventralization | (Gavino and Reddien, 2011; Molina et al., 2011) |
| nlg-8 | ventralization | (Molina et al., 2011) |
| tolloid | dorsal ruffling, ML-regeneration defective | (Reddien et al., 2007) |
| ndl-3 | two pharynges | (Lander and Petersen, 2016; Scimone et al., 2016) |
| nog-1 | dorsalization | (Molina et al., 2011) |
| glypican-1 | indented heads; midline defect | (Wenemoser et al., 2012) |
| netrin-2 | CNS defects | (Cebria and Newmark, 2005) |
| ptk7 | two pharynges | (Lander and Petersen, 2016) |
| ndk | posterior expansion of eyes and brain | (Cebria et al., 2002) |
| slit | medialization | (Cebria et al., 2007; Gurley et al., 2010; Oderberg et al., 2017) |