Table 1. Characteristics and ocular signs and symptoms among patients with confirmed acute toxoplasmosis infection at baseline examination, Brazil*.
| Characteristics |
Total, n = 52 |
No ocular involvement, n = 40 |
Ocular involvement, n = 12 |
p value |
|---|---|---|---|---|
| Age at infection, y, median (IQR)† | 34 (27–40) | 32 (22–38) | 43 (40–47) | <0.01 |
| >40 years of age† | 14 (27) | 6 (15) | 9 (75) | <0.01 |
| Sex | ||||
| M | 44 (84.6) | 33 (82.5) | 11 (91.7) | 0.50 |
| F |
8 (15.4) |
7 (17.5) |
1 (8.3) |
0.50 |
| Follow-up length, mo, median (IQR) |
36 (19–36) |
36 (12–36) |
35 (24–37) |
0.32 |
| Underlying conditions | ||||
| Arterial hypertension | 7 (13.5) | 4 (10.0) | 3 (25.0) | 0.23 |
| Diabetes mellitus |
1 (1.9) |
0 |
1 (8.3) |
0.23 |
| General signs and symptoms | ||||
| Fever | 49 (94.2) | 38 (95.0) | 11 (91.7) | 0.68 |
| Headache | 33 (63.5) | 25 (62.5) | 8 (66.7) | 0.81 |
| Myalgia | 30 (57.7) | 22 (55.0) | 8 (66.7) | 0.50 |
| Lymphadenopathy |
8 (15.4) |
7 (17.5) |
1 (8.3) |
0.50 |
| Ocular signs and symptoms | ||||
| VA at baseline, logMAR, median (IQR)†‡ | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.1 (0.0–0.6) | 0.01 |
| Eye pain | 8 (15.4) | 5 (12.5) | 3 (25.0) | 0.33 |
| Self-reported recent reduction of VA† | 10 (19.2) | 1 (2.5) | 9 (75.0) | <0.01 |
| Floaters† | 3 (5.7) | 0 | 3 (25.0) | 0.01 |
*Values are no. (%), except as indicated. Mann-Whitney-Wilcoxon test was used to compare continuous and the mid-p exact tests for proportions between subgroups. IQR, interquartile range; logMAR, logarithm of the Minimum Angle of Resolution scale; VA, visual acuity. †Statistical significant at α = 5%. ‡For visual acuity baseline, binocular involvement was considered the worst VA.