Figure 1.

Susceptibilities of 13 bat cell lines to infection by SARS-CoV (A) and SARS-CoV-2 (B) shown from harvest of supernatants and cell lysates at day 0 and 5 postinfection. Viral titers and β-Actin mRNA were determined by real-time quantitative reverse transcription PCR. Viral load is expressed as normalized fold change in log₁₀. Error bars indicate SDs of triplicate samples. Bat cell lines are listed by species and organ. Vero cells served as controls. Asterisk (*) indicates p<0.05 and increase in viral load >1 log₁₀. Mp, Miniopterus pusillus, Mr, Myotis ricketti; Pa, Pipistrellus abramus, Rl, Rousettus leschenaultii, Rs, Rhinolophus sinicus, Tp, Tylonycteris pachypus. SARS-CoV, severe acute respiratory syndrome coronavirus.