Table 2.
Comparison of RBANS Scores Between First-Episode Schizophrenia Patients and Healthy Control Subjects
Cognitive Index | DNFE Patients n = 256 | Controls n = 180 | F(P)a | Effect Size | MD (95% CI) |
---|---|---|---|---|---|
Immediate memory | 65.3 ± 16.9 | 75.6 ± 17.6 | 57.4 (<.001) | 0.60 | −10.3 (−7.6 to −13.0) |
Visuospatial/constructional | 77.4 ± 16.9 | 79.8 ± 15.4 | 3.4 (.066) | 0.15 | −2.3 (0.16 to −4.78) |
Language | 75.2 ± 18.3 | 94.1 ± 13.2 | 249.4 (<.001) | 1.15 | −18.9 (−16.6 to −21.3) |
Attention | 74.7 ± 19.9 | 87.5 ± 19.9 | 66.5 (<.001) | 0.64 | −12.7 (−9.7 to −15.8) |
Delayed memory | 69.8 ± 20.1 | 86.5 ± 15.0 | 0.92 | −16.6 (−14.0 to −19.2) | |
Total | 66.6 ± 15.9 | 80.2 ± 15.0 | 154.0 (<.001) | 0.88 | −13.5 (−11.2 to −15.9) |
Note: Adjusted F value controlling for gender, age, education, smoking status, and BMI between patients and control subjects; MD, mean difference between patients and health controls; CI, confidence interval.
The measure of effect size refers to Cohen’s d value here. Since Cohen suggested that d = 0.2 be considered a “small” effect size, 0.5 a “medium” effect size and 0.8 a “large” effect size, most of RBANS domain and total scores between patients and controls display large difference except for immediate memory (medium) and visuospatial/construction (small).