Table 2.
Positive predictive value (PPV) and negative predictive value (NPV) to diagnose appendicitis (selection of the items that were used in the evaluated appendicitis scores) in the entire cohort of children with abdominal pain.
| Present | PPV % (CI 95%) | NPV % (CI 95%) | |
|---|---|---|---|
| Continuous pain | 7/463 | 40.0 (8.0–79.9) | 50.0 (34.0–69.9) |
| Nausea/vomiting | 319/463 | 81.5 (78.4–84.5) | 45.3 (38.7–51.7) |
| Anorexia | 176/463 | 82.1 (76.2–87.4) | 38.0 (32.0–43.4) |
| Migration of pain | 0/463 | / | / |
| Temperature (>38.5°C) | 312/463 | 97.4 (85.0–99.9) | 30.0 (28.8–30.3) |
| Tenderness RLQ | 334/463 | 73.3 (72.5–73.9) | 58.3 (28.9–83.4) |
| Rebound tenderness | 293/463 | 89.7 (85.3–93.2) | 36.5 (32.4–39.8) |
| Cough/hopping tenderness | 205/463 | 89.7 (86.0–93.0) | 37.2 (29.0–44.5) |
| Leukocytosis (>11 mrd/L) | 333/463 | 85.7 (82.4–88.7) | 48.8 (43.3–53.9) |
| Neutrophilia (>7.9 mrd/L or >75%) | 72/463 | 96.4 (92.5–99.3) | 13.6 (4.0–21.1) |
| CRP (>20 mg/L) | 332/456 | 94.6 (91.1–96.9) | 47.7 (44.4–49.9) |
| US demonstrating APP | 287/456 | 95.9 (93.0–97.8) | 68.1 (63.8–70.9) |
RLQ, right lower quadrant; CRP, C-reactive protein; US, ultrasound; APP, appendicitis.