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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Cell Rep. 2020 Sep 15;32(11):108151. doi: 10.1016/j.celrep.2020.108151

Figure 4. Cyclin D1 Augments Phosphorylation of Akt1 at Ser473.

Figure 4.

(A–D) Immunohistochemical staining of 3T3 cells (A), cyclin D1−/− 3T3 cells (B), or cyclin D1−/− 3T3 cells transduced with retrovirus encoding either cyclin D1WT (C) or cyclin D1KE (D). Immunohistochemical staining with Z slice reconstruction to show staining with antibody as indicated. Cyclin D1 co-localizes with pAkt1 Ser473 at the cytoplasmic membrane and is enriched at focal contacts.