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. 2020 Oct 2;61(12):1629–1644. doi: 10.1194/jlr.RA120000924

Fig. 6.

Fig. 6.

Coordinated regulation of hepatic 25-HC and 26-HC levels in WT mice. Eight-week-old C57Bl/6J mice were harvested, and their hepatic mRNA, oxysterols, and serum insulin were determined. The mice had free access to RC diet (CE-2, CLEA Japan Inc) until being euthanized. Each dot in the graphs represents one mouse (n = 6). A: Correlation of plasma insulin level to hepatic Cyp7b1 mRNA expression level of freely fed C57Bl/6J mice. B: Correlation of hepatic 26-HC to Cyp7b1 mRNA expression level. C: Correlation hepatic 25-HC level to Ch25h mRNA expression level. D: Correlation of hepatic 26-HC and 25-HC levels.