TABLE 1.

Possible candidates that may mediate cholesterol transport to and from RBCs

Name	Keyword	Transcriptomics (Normalized Signal)	Proteomics (Copy Number)	Function in Lipid or Lipoprotein Metabolism
Phospholipase A2 activating protein (PLAA)	Lipase	421.1 ± 140.2	604.4 ± 509.2	Ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner (40).
				Regulation of cytosolic and calcium-independent phospholipase A2 activities and prostaglandin E2 biosynthesis (41).
ABCA7	ATP binding cassette	988.6 ± 161.7	1,635.8 ± 1,297.1	The function is not known; the expression pattern suggests a role in lipid homeostasis (42).
Phospholipid scramblase 1 (PLSCR1)	Lipid	677.8 ± 280.2	6,339.9 ± 1,723.8	ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions, regulation of phospholipid asymmetry in the plasma membrane (43).
Proteolipid protein 2 (PLP2)	Lipid	1,112.7 ± 326.0	2,048.9 ± 1,260.4	Unknown
LDLR class A domain containing 4 (LDLRAD4)	Lipoprotein	534.9 ± 275.0	248.7 ± 289.7	Unknown