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. 2020 Dec 1;15(12):e0243037. doi: 10.1371/journal.pone.0243037

Table 4. Risk of vertebral fracture in women with hysterectomy compared with the comparison group stratified by follow-up year.

Comparison group Hysterectomy Crude Adjusted*
Follow time N Event PY IR N Event PY IR HR (95% CI) p-value HR (95% CI) p-value
<5 32189 54 148499 0.36 8267 59 39044 1.51 4.37 (3.02,6.33) <0.001 4.33 (2.99,6.28) <0.001
5–9 32135 47 114049 0.41 8208 49 30847 1.59 4.09 (2.74,6.10) <0.001 3.89 (2.60,5.82) <0.001
≧9 32088 13 138354 0.09 8159 19 38228 0.50 5.71 (2.82,11.55) <0.001 5.42 (2.66,11.01) <0.001

PY: Person-years; IR: Incidence rate per 1,000 person-years; HR: Hazard ratio; CI: Confidence interval.

*: Model was adjusted for age, urbanization, insurance premium occupation, estrogen treatment, and Charlson comorbidity index.