Fig 3. PS, GPR37, and GPR37L1 immunoreactivity (IR) with DAB staining on days 1, 3, and 7 after facial nerve transection.
PS-IR decreased slightly on day 1 (a), but increased moderately on day 3, and increased strongly on day 7 (c). Some motoneurons showed very intense PS-IR signal (arrows), whereas others were moderate. GPR37-IR showed a weak increase in the motoneurons on the operated side on days 1, 3, and 7 (e, f, g) compared with the levels on the untreated side (h). GPR37 L1-IR signal was observed in glial cells (arrows) around the motoneurons of the facial nucleus predominately on the operated side on day 7 (k), but not on the untreated side (l) or on days 1 or 3 (i, j). The numbers on the bars indicate the scale in microns.