Table 2.
Summary of current single cell RNA-seq studies on human placenta.
| Gestational age (weeks) | Tissue | Number of cells | Number of placenta | Single cell isolation | Platform | Average reads length (bp) | Mean Pair-end reads | Reference |
|---|---|---|---|---|---|---|---|---|
| 6–11 | Villous, decidual | 14,341 6754 |
9 | Enzyme | 10x Drop-seq | 100 | N/A | Suryawanshi et al. (2018) |
| 6–14 | Placenta, blood | 70,000 | 5 | Enzyme, FACS | 10x Smart-seq2 | 75 | 1 × 106 | Vento-Tormo et al. (2018) |
| 8, 24 | Placenta | 1,567 | 8 | Enzyme, gradient centrifugation, MACS | Smart-seq2 | 150 | 1 × 106 | Liu et al. (2018) |
| 11–13 | Placenta | 7245 | 10 | Enzyme | 10x | N/A | N/A | Sun et al. (2019) |
| Term | Placenta | 87 | 2 | Enzyme, gradient centrifugation | Fluidigm | 75 | 3.65 × 106 | Pavličev et al. (2017) |
| Term (preeclampsia or healthy) | Placenta, blood | 24,000 | 8 | Enzyme | 10x | 130 | 35800 | Tsang et al. (2017) |
| Term (with or without labor) preterm (33–35 weeks) | Placenta | 79,906 | 9 | Enzyme | 10x | N/A | N/A | Pique-Regi et al. (2019) |
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