Table 2.

Univariate and multivariate analysis of clinicopathologic factors associated with DFS in PTC cases.

Patient characteristics	Univariate analysis	Multivariate analysis
	P value	HR	95% CI	P value
Age
<55 vs
≥55	0.736	1.986	0.546–7.226	0.298
Sex
Male vs
Female	0.362	1.258	0.281–5.643	0.764
TNM stage
I vs II vs
III vs IV	0.061	1.043	0.488–2.231	0.913
Tumour size
<2 cm vs
≥2 cm	0.327	0.956	0.253–3.608	0.947
Multifocality
Present vs
Absent	0.128	2.340	0.604–9.063	0.219
Extrathyroidal extension
Present vs
Absent	0.154	1.050	0.260–4.241	0.945
Lymphovascular invasion
Present vs
Absent	0.004*	2.826	0.416–19.188	0.288
Lymph node metastases
Present vs
Absent	0.006*	1.819	0.441–7.515	0.408
Concurrent Hashimoto’s thyroiditis
Present vs
Absent	0.424	0.900	0.242–3.346	0.875
PD-L1
Negative vs
Positive	0.048*	3.053	0.599–15.552	0.179
CD8
Negative vs
Positive	0.028*	0.536	0.135–2.130	0.376
EMT status
E-cadneg/Vimneg vs
E-cadneg/Vimpos vs
E-cadpos/Vimneg vs
E-cadpos/Vimpos	0.026*	3.132	1.102–8.897	0.032*