Figure 2.

Signaling questions with respect to ROB domains across studies. Bars from low/high/unclear ROB are stacked to be 100%. Domains are described on the right-hand side. The number on the bar is the number of low ROB studies (total LR/non-LR/both at top) based on a single signaling question summarized as a term on the left-hand side. LR: logistic regression; ROB: risk of bias.