Table 5.
Risk of Adverse Neonatal Outcomes Associated with IDIa
| IDI (months)b | Adjusted RR (95% CI)c | ||||||
|---|---|---|---|---|---|---|---|
| 6–17 N (%) |
18–36 N (%) |
37–60 N (%) |
61–180 N (%) |
6–17 vs. 18–36 | 37–60 vs. 18–36 | 61–180 vs. 18–36 | |
| Deliveries, N | 17,392 | 91,670 | 50,447 | 22,273 | |||
| LBW (< 2500 g) | 3705 (21.4) | 12,643 (13.8) | 5941 (11.8) | 2864 (12.9) | 1.38 (1.32, 1.44) | 1.02 (0.99, 1.05) | 1.22 (1.17, 1.27) |
| VLBW (< 1500 g) | 572 (3.3) | 1128 (1.2) | 567 (1.1) | 296 (1.3) | 2.35 (2.10, 2.62) | 1.10 (1.01, 1.21) | 1.47 (1.32, 1.64) |
| Preterm | 3934 (22.7) | 13,067 (14.3) | 6403 (12.8) | 2789 (12.6) | 1.44 (1.39, 1.50) | 0.97 (0.94, 1.00) | 1.06 (1.02, 1.10) |
| Congenital anomalies | 36 (0.2) | 166 (0.2) | 94 (0.2) | 42 (0.2) | 1.08 (0.78, 1.50) | 1.13 (0.88, 1.45) | 1.11 (0.78, 1.59) |
| Neonatal hospitalization | 378 (2.5) | 1518 (1.9) | 742 (1.7) | 470 (2.4) | 1.24 (1.11, 1.38) | 1.02 (0.94, 1.12) | 1.28 (1.15, 1.43) |
|
Stillbirth, N (Rate/1000) |
792 (45.6) | 2219 (24.2) | 1246 (24.7) | 644 (28.9) | 1.70 (1.56, 1.86) | 1.14 (1.08, 1.22) | 1.50 (1.38, 1.62) |
|
Neonatal death < 28 days, N (Rate/1000) |
731 (44.1) | 1848 (20.7) | 929 (18.9) | 456 (21.1) | 1.89 (1.74, 2.05) | 1.04 (0.97, 1.13) | 1.25 (1.14, 1.38) |
aFetal/Neonatal outcomes are calculated at the maternal level if at least one fetus/neonate has the outcome
bColumns present N (%) for each adverse delivery outcome within each IDI category, with the exception of stillbirth and neonatal death < 28 days which are presented as rate/1000 deliveries
cRelative risks and 95% confidence intervals from a logistic model with generalized estimating equations to account for the correlation of outcomes within cluster adjusting for maternal age, maternal education, parity, ANC visits, and iron supplements. Very low birthweight (< 1500) and Stillbirth outcomes used a Poisson distribution, all other Fetal/Neonatal outcomes used a Binomial distribution