Table 1.
Demographics of patients and characteristics of bloodstream infection
| Characteristic | |
|---|---|
| Male | 52 (48%) |
| Median age, years | 71 (IQR 57, 83) |
| Median days in hospital before bloodstream infection | 0 (IQR 0, 1) |
| Median inpatient days after bloodstream infection | 8 (IQR 5, 12) |
| Number admitted to OPAT | 38 (35%) |
| Polymicrobial bloodstream infectiona | 6 (6%) |
| Source of infection | |
| Complicated UTI | 46 (43%) |
| Uncomplicated UTI | 35 (32%) |
| Intra-abdominal other than biliary tract | 11 (10%) |
| Biliary tract | 7 (6%) |
| Febrile neutropenia | 4 (4%) |
| No focus | 4 (4%) |
| Native osteomyelitis | 1 (1%) |
| Total duration of antimicrobial therapy, median, days | 15 (IQR 12, 17) |
| Number treated with carbapenem | 102 (94%) |
| Number de-escalated to oral therapyb | 45 (42%) |
| Median duration oral therapy, days | 12 (IQR 6, 15) |
| 30-day mortalityc | 11/99 (11%) |
OPAT outpatient antimicrobial therapy, UTI urinary tract infection
a 1 patient was bacteremic with both S. agalactiae and P. mirabilis, 2 patients had Staphylococcus aureus, 1 patient had Streptococcus anginosus group, 1 patient had Pseudomonas aeruginosa, 1 patient had Enterococcus raffinosus
b 29 patients given ciprofloxacin, 10 trimethoprim-sulfamethoxazole, 3 trimethoprim, 2 oral fosfomycin, 1 nitrofurantoin,
c 30-day follow-up not available for 9 patients