Table 2.
Genotype and allele Distributions of Investigated SNPs in Pediatric Population
| SNP | Genotype/Allele | Control | BMI>1 SD | OR (95% CI, p) |
|---|---|---|---|---|
| RBP4 rs3758539 | CC | 54 (25.35%) | 87 (40.84%) | |
| CT | 26 (12.20%) | 33 (15.49%) | 0.787 (0.425–1.459, p= 0.547) | |
| TT | 1 (0.46%) | 6 (2.81%) | 3.724 (0.436–31.799, p=0.377) | |
| CT+TT | 27 (12.67%) | 39 (18.30%) | 0.896 (0.493–1.629, p=0.836) | |
| C allele | 134 (82.71%) | 207 (82.14%) | ||
| T allele | 28 (17.28%) | 45 (17.85%) | 1.040 (0.618–1.749, p=1.000) | |
| RBP4 rs10882280 | CC | 67 (31.45%) | 97 (45.53%) | |
| AC | 14 (6.57%) | 26 (12.20%) | 1.283 (0.624–2.637, p=0.618) | |
| AA | 0 (0%) | 3 (1.40%) | 4.846 (0.246–95.42, p= 0.403) | |
| AA+AC | 14 (6.57%) | 29 (13.61%) | 1.431 (0.703–2.910, p=0.414) | |
| C allele | 148 (91.35%) | 220 (87.30%) | ||
| A allele | 14 (8.64%) | 32 (12.69%) | 1.538 (0.793–2.981, p=0.261) | |
| STRA6 rs974456 | CC | 51 (23.94%) | 78 (36.61%) | |
| CT | 24 (11.26%) | 38 (17.84%) | 1.035 (0.556–1.927, p=0.912) | |
| TT | 6 (2.81%) | 10 (4.69%) | 1.090 (0.373–3.184, p=0.875) | |
| CT+TT | 30 (14.08%) | 48 (22.53%) | 1.046 (0.587–1.863, p=0.994) | |
| C allele | 126 (77.77%) | 194 (76.98%) | ||
| T allele | 36 (22.22%) | 58 (23.01%) | 1.046 (0.652–1.679, p=0.904) | |
| STRA6 rs351224 | TT | 23 (10.79%) | 40 (18.77%) | |
| AT | 42 (19.71%) | 56 (26.29%) | 0.616 (0.317–1.196, p=0.200) | |
| AA | 16 (7.5%) | 30 (14.08%) | 1.078 (0.487–2.387, p=0.852) | |
| AT + TT | 58 (27.23%) | 86 (40.37%) | 0.852 (0.462–1.572, p=0.721) | |
| T allele | 88 (54.32%) | 136 (53.96%) | ||
| A allele | 74 (45.67%) | 116 (46.03%) | 1.014 (0.682–1.507, p=1.000) |