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. 2020 Nov 27;13:1007–1020. doi: 10.2147/JIR.S285714

Figure 2.

Figure 2

miR-21 promotes angiotensin II (Ang II)-induced myofibroblast transformation in vitro. (AC) Western blotting analysis of myofibroblast markers in wild-type (WT) and miR-21 knockout (KO) primary cardiac fibroblasts (CFs) treated with or without Ang II. Left panel (A), representative blots; right panel (B and C), quantitative analysis; *P < 0.05 and ****P < 0.0001, n = 3 per group. (D) Representative immunofluorescence staining image of α-SMA and FAP in WT and miR-21 KO primary CFs treated with or without Ang II. Scale bar = 100 µm.

Abbreviation: ns, not significant.