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. 2020 Nov 27;13:12269–12279. doi: 10.2147/OTT.S278954

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© 2020 Liu et al.

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The invasion rate of Bel7404 and HepG2 cells in the let-7a-5p mimic group was lower than that in the let-7a-5p control group; the invasion rate of Bel7404 and HepG2 cells in the sh-let-7a-5p group was higher than that in the shControl group (A). Quantitative analysis of migration ability in Bel7404 cells (B). Quantitative analysis of migration ability in HepG2 cells (C). *Indicates that the difference between the treated and control cells was statistically significant (P < 0.05). ***Indicates that the difference between the treated and control cells was statistically significant (P < 0.001). The ability of human hepatoma cells to penetrate the Matrigel can indicate cell invasion capacity.