Table 1.
Clinical and biochemical characteristics of the obese population in comparison with control group.
| Parameters | Obese population n = 85 | Control group n = 35 | p- value |
|---|---|---|---|
| Age (years) | 44 ± 9.8 | 45 ± 11 | 0.14 |
| Sex (M/F) | 17/68 | 12/23 | 0.03* |
| Body mass index (kg/m2) | 42.5 ± 4.8 | 23.2 ± 3.7 | 0.0001 |
| Waist circumference (cm) | 126.1 ± 12.8 | 90.1 ± 11.2 | 0.0001 |
| Systolic blood pressure (mmHg) | 129.6 ±14 | 122 ± 12.3 | 0.35 |
| Diastolic blood pressure (mmHg) | 84.3 ± 13.9 | 74.3 ± 10.1 | 0.04 |
| Total cholesterol (mg/dl) | 195.7 ± 33.5 | 178.7 ± 22.9 | 0.04 |
| HDL- cholesterol (mg/dl) | 47.4 ± 10.7 | 56 ± 14.2 | 0.01 |
| LDL- cholesterol (mg/dl) | 119.4 ± 31.3 | 90.1 ± 21.4 | 0.01 |
| Triglycerides (mg/dl) | 140.9 ± 66.5 | 88.9 ± 39.3 | 0.001 |
| Fasting blood glucose (mg/dl) | 100.3 ± 22.9 | 85.7 ± 10.2 | 0.006 |
| Glycosylated hemoglobin (%) | 5.5 ± 1.1 | – | – |
| Fasting blood insulin(IU/ml) | 13.2 ± 7.2 | – | – |
| HOMA-IR | 3.25 ± 1.87 | – | – |
| HOMA-β% | 162.1 ± 110.5 | – | – |
| Aspartate aminotransferase (IU/l) | 27.8 ± 14.3 | 20.1 ± 3.6 | 0.05 |
| Alanine aminotransferase (IU/l) | 36.1 ± 25.1 | 22.9 ± 10.4 | 0.08 |
| Serum Granzyme B (pg/ml) | 28.16 ± 18.5 | 8.3 ± 15.27 | 0.001 |
| Type 2 Diabetes (%) | 18% | 0 | 0.0001* |
| Impaired fasting glucose (%) | 9% | 0 | 0.07* |
| Metabolic syndrome(%) | 88% | 0 | 0.02* |
Student’s T test; *Chi-square test.