Table 5.
Correlation between serum Granzyme B (GrB) levels and clinical and biochemical parameters in obese subjects (n = 85).
| Correlation coefficient | p-value | |
|---|---|---|
| Age (years) | 0.06 | 0.64 |
| Sex (M/F) | 0.18 | 0.58 |
| Body mass index (kg/m2) | 0.58 | 0.001 |
| Waist circumference (cm) | 0.37 | 0.05 |
| Systolic blood pressure (mmHg) | 0.11 | 0.72 |
| Diastolic blood pressure (mmHg) | 0.27 | 0.11 |
| Total cholesterol (mg/dl) | 0.19 | 0.59 |
| HDL- cholesterol (mg/dl) | 0.31 | 0.44 |
| LDL- cholesterol (mg/dl) | 0.23 | 0.13 |
| Triglycerides (mg/dl) | 0.55 | 0.02 |
| Fasting blood glucose (mg/dl) | 0.37 | 0.05 |
| Glycosylated hemoglobin (%) | 0.11 | 0.13 |
| Fasting blood insulin (IU/ml) | 0.14 | 0.45 |
| HOMA-IR | 0.39 | 0.09 |
| HOMA-β% | 0.19 | 0.33 |
| Aspartate aminotransferase (IU/l) | 0.11 | 0.54 |
| Alanine aminotransferase (IU/l) | 0.06 | 0.73 |
| Serum GrB levels (pg/ml) | 0.31 | 0.04 |
| Type 2 diabetes (%) | 0.21 | 0.08 |
| Impaired fasting glucose (%) | 0.38 | 0.04 |
| Metabolic syndrome (%) | 0.35 | 0.05 |
Bivariate correlation analyses (Spearman’s coefficient).