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. 2020 Nov 18;11:588149. doi: 10.3389/fendo.2020.588149

Table 5.

Subgroup analysis of the associations between AKI and the thyroid hormone.

Crude Model Model Ⅰ Model ⅠⅠ P for interaction
OR(95%CI) P-value OR(95%CI) P-value OR(95%CI) P-value
TT3 (nmol/L) <0.01*
Normal TSH 0.04 (0.004, 0.45) <0.01* 0.04 (0.004, 0.55) 0.02* 0.001 (0.001, 0.16) <0.01*
Lower TSH 46.95 (0.61, 3632.43) 0.08 203.57(1.12, 36874.33) 0.06 150.69 (0.29, 77935.173) 0.12
FT3 (pmol/L) 0.01*
Normal TSH 0.43(0.18, 0.99) 0.05 0.57 (0.23, 1.38) 0.21 0.22 (0.05, 1.07) 0.06
Lower TSH 1.86(0.56, 6.20) 0.31 2.22 (0.61, 8.00) 0.22 1.79 (0.24, 13.42) 0.57
TT4 (nmol/L) 0.67
Normal TSH 0.98 (0.95, 1.00) 0.10 0.98 (0.96, 1.01) 0.28 0.97 (0.93, 1.01) 0.14
Lower TSH 0.99 (0.96, 1.04) 0.84 0.99 (0.95, 1.04) 0.63 0.95 (0.87, 1.04) 0.27
FT4 (pmol/L) 0.20
Normal TSH 1.00 (0.81, 1.23) 0.99 0.99(0.79, 1.23) 0.89 1.08 (0.79, 1.49) 0.62
Lower TSH 0.93 (0.69, 1.26) 0.65 0.95(0.69, 1.31) 0.74 0.76 (0.47, 1.23) 0.26

Crude model adjusted for: None.

Model I adjusted for: sex; age (years); body mass index (kg/m2).

Model II adjusted for: sex; age (years); body mass index (kg/m2); platelet (G/L); Hematocrit (%); creatinine (μmol/L); intraoperative transfusion of packed red blood cell (u); aortic cross-clamping time (min); circulatory arrest time (min).

*P value indicates significance at P < 0.05.