Table 1.
Anthropometric and biochemical characteristics of the subjects
| Control | HF post-AMI | Non-HF post-AMI | HF | CAD | P value | |
|---|---|---|---|---|---|---|
| Male (n, %) | 13 (43) | 42 (55) | 33 (57) | 19 (49) | 22 (49) | 0.712 |
| Age (years) | 59.63. ± 10.39 | 63.36 ± 7.29 | 62.84 ± 11.12 | 61.69 ± 7.18 | 64.36 ± 7.68 | 0.189 |
| BMI (kg/m2 ) | 24.49 ± 3.16 | 23.91 ± 2.76 | 23.77 ± 4.08 | 24.05 ± 4.04 | 26.06 ± 4.72 | 0.019 |
| Smoking history (n, %) | 10 (33) | 43 (57) | 22 (38) | 10 (26) | 13 (29) | 0.060 |
| Diabetic (n, %) | 9 (30) | 30 (39) | 17 (28) | 11 (28) | 14 (31) | 0.663 |
| Hypertensive (n, %) | 22 (73) | 54 (71) | 41 (71) | 28 (72) | 35 (78) | 0.935 |
| TG (mmol/L) | 1.43 ± 0.71 | 1.36 ± 1.10 | 1.57 ± 0.75 | 1.07 ± 0.54 | 1.68 ± 0.92 | 0.016 |
| TC (mmol/L) | 4.41 ± 1.16 | 4.27 ± 1.04 | 4.50 ± 1.07 | 4.01 ± 1.10 | 4.42 ± 1.50 | 0.315 |
| LDL-C (mmol/L) | 2.70 ± 0.95 | 2.78 ± 0.93 | 2.97 ± 0.88 | 2.41 ± 1.00 | 2.68 ± 1.37 | 0.127 |
| HDL-C (mmol/L) | 1.08 ± 0.23 | 1.01 ± 0.27 | 1.00 ± 0.45 | 1.09 ± 0.39 | 1.04 ± 0.34 | 0.642 |
| SCr (umol/L) | 68 (52, 86) | 73 (60, 91) | 66 (50, 80) | 94 (79, 119) | 68 (59, 79) | 0.313 |
| UN (umol/L) | 0.90 (0.74, 1.12) | 5.3 (3.98, 6.89) | 4.66 (3.86, 5.99) | 7.83 (4.57, 10.34) | 5.15 (4.22, 6.22) | 0.806 |
| CysC (mg/L) | 5.22 (4.16, 7.44) | 1.11 (0.93, 1.37) | 0.81 (0.74, 1.04) | 1.17 (0.96, 1.50) | 0.93 (0.81, 1.14) | <0.01** |
| eGFR (mL/min/1.73 m2) | 90 (67, 96) | 89 (67, 98) | 94 (84.5, 102) | 75 (48, 88) | 89 (82, 98) | 0.112 |
| LVEF (%) | 60.83 ± 6.86 | 55.59 ± 8.71 | 61.46 ± 5.27 | 54.61 ± 8.53 | 64.01 ± 6.25 | < 0.001*** |
| LVFS (%) | 32.63 ± 4.76 | 29.31 ± 5.55 | 33.03 ± 3.75 | 29.01 ± 5.89 | 35.13 ± 4.75 | < 0.001*** |
| LVEDD (mm) | 47.47 ± 5.15 | 47.89 ± 5.74 | 47.45 ± 4.66 | 52.03 ± 8.98 | 47.44 ± 4.90 | <0.01** |
| Postoperative NT-proBNP (ng/L) | 41 (20, 100) | 2136 (1487, 3461) | 249 (151.5, 442) | 2645 (1903, 3678) | 120 (20, 378) | < 0.001*** |
| Intraprocedural NT-proBNP (ng/L) | / | 478 (134, 950) | 204 (20.1, 434.5) | / | / | < 0.001*** |
| TnI | 0.02 ± 0.03 | 18.75 ± 27.71 | 11.28 ± 21.94 | 0.03 ± 0.02 | 0.26 ± 1.30 | < 0.001*** |
| TIMI | / | 2.66 ± 0.88 | 2.64 ± 0.77 | / | / | 0.822 |
| Number of branch lesions | / | 1.01 ± 1.37 | 1.17 ± 1.40 | / | / | 0.511 |
| Immediate diagnosis of lncRNA-NRF | 0.95 (0.87, 1.02) | 1.71 (1.21, 2.02) | 0.56 (0.48, 0.61) | 1.07 (0.93, 1.29) | 0.67 (0.59, 0.86) | < 0.001*** |
| Intraprocedural of lncRNA-NRF | / | 1.77 (1.32, 3.50) | 1.01 (0.83, 1.14) | / | / | < 0.001*** |
| Postoperative 4 h of lncRNA-NRF | / | 1.18 (0.87, 1.63) | 0.66 (0.56, 0.74) | / | / | < 0.001*** |
| Postoperative 12 h of lncRNA-NRF | / | 1.34 (0.93, 1.52) | 0.83 (0.65, 1.00) | / | / | < 0.001*** |
| Postoperative 24 h of lncRNA-NRF | / | 1.07 (0.98, 1.47) | 0.98 (0.86, 1.06) | / | / | < 0.001*** |
| Postoperative 72 h of lncRNA-NRF | / | 1.01 (0.89, 1.29) | 0.95 (0.80, 1.04) | / | / | <0.01** |
Results are expressed as mean ± standard deviation, median (interquartile range) or n (%). BMI, body mass index; TG, triglycerides; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; SCr, serum creatinine; CysC, cystatin; UN, urea nitrogen; eGFR, estimated glomerular filtration rate; NT-proBNP, N-terminal pro-brain natriuretic peptide; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; LVEDD, left ventricular end-diastolic dimension’ TnI, troponin I; TIMI, thrombolysis in myocardial infarction
*P < 0.05, **P < 0.01, ***P < 0.001