Skip to main content
. 2020 Oct 9;8(6):419–431. doi: 10.1007/s40336-020-00393-x

Table 2.

Mixed-effects generalised linear modeling showing the unadjusted, multivariable and bootstrapped multivariable effect estimates of co-variables on fractional anisotropy and mean diffusivity of the roots of the brachial plexus

DTI parameter Experimental factors Unadjusted coefficients (95% CI) p value Adjusted coefficients (95% CI) p value Resampled adjusted coefficients (95% CI) Resampled p value
Fractional anisotropy SNR 0.0001 (− 0.0003, 0.0004) 0.662 0.0001 (− 0.0001, 0.0004) 0.257 0.0001 (− 0.001, 0.002) 0.840
Age in years 0.0003 (− 0.006, 0007) 0.926 0.001 (0.001, 0.002) 0.001 0.001 (− 0001, 0.003) 0.236
Number of diffusion directions − 0.002 (− 0.005, 0001) 0.183 − 0.001 (− 0.002, − 0.001)  < 0.001 − 0.001 (− 0.002, − 0.0004) 0.002
Echo time (ms) 0.002 [0.00001, 0.004]) 0.174 a a a a
b value (mm/s) − 0.0004 (− 0.001, 0.0001) 0.098 a a a a
Resolution (mm3) 0.008 (0.003, 0.013) 0.126 a a a a
Mean diffusivity (mm2/s × 10–3) SNR − 0.001 (− 0.003, 0.0005) 0.154 − 0.001 (− 0.003, 0) 0.055 − 0.001 (− 0.012, 0.01) 0.799
Age in years − 0.01 (− 0.03, 0.01) 0.303 − 0.025 (− 0.030, − 0.021)  < 0.001 − 0.03 (− 0.042, − 0.01) 0.003
Number of diffusion directions 0.005 (− 0003, 0013) 0.234 0.001 (− 0.001, 0.002) 0.238 0.001 (− 0.005, 0.006) 0.723
Echo time (ms) − 0.012 (− 0.019, − 0.005) 0.174 a a a a
b value (mm/s) 0.001 (0.0004, 0.002) 0.003 a a a a
Resolution (mm3) 0.004 (0.002, 0.007) 0.562 a a a a

aExcluded due to multicollinearity