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. 2020 Nov 18;10:605386. doi: 10.3389/fonc.2020.605386

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Copyright © 2020 Montalvo-Casimiro, González-Barrios, Meraz-Rodriguez, Juárez-González, Arriaga-Canon and Herrera

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Advantages of pharmacological epi-drug repurposing in clinical applications. Drug repurposing serves as a shortcut reducing the time of incorporating a drug into the clinic; since the preclinical phase has already been carried out previously, giving a second chance to old drugs. Initially, it reduces the cost of development and toxicity research, which leads to greater cost-benefit efficiency for the pharmaceutical industry by generating a new cancer therapy. The repositioning of epi-drugs is a promise for the generation of new drugs of precision medicine.