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. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: Neurotoxicology. 2020 Jul 28;81:1–10. doi: 10.1016/j.neuro.2020.07.007

Table 2.

Total mercury concentration (ppm) in pup tissue at postnatal day (PND) 6, 21, or 60

Female					Male
MeHg	Blood	Brain	Muscle	P	Blood	Brain	Muscle	P
PND 6
0 ppm	0.005 ± 0.003	0.010 ± 0.003	0.103 ± 0.018	^a, ^f, ^g	0.001 ± 0.001	0.004 ± 0.000	0.083 ± 0.026	^c, ^f, ^g
0.5 ppm	0.114 ± 0.037	0.218 ± 0.015	0.447 ± 0.044	^a, ^f, ^g	0.078 ± 0.016	0.200 ± 0.009	0.446 ± 0.040	^a, ^e, ^f, ^g
5 ppm	1.267 ± 0.103	3.175 ± 0.348	3.466 ± 0.380	^d, ^g	1.080 ± 0.175	2.720 ± 0.350	2.966 ± 0.139	^b, ^e, ^g
PND 21
0 ppm	0.008 ± 0.003	0.000 ± 0.000	0.014 ± 0.006	ns	0.006 ± 0.001	0.001 ± 0.000	0.005 ± 0.002	^d, ^e, ^g
0.5 ppm	0.150 ± 0.006	0.069 ± 0.005	0.193 ± 0.010	^a, ^e, ^f, ^g	0.093 ± 0.009	0.077 ± 0.005	0.171 ± 0.014	^a, ^f, ^g
5 ppm	0.897 ± 0.150	0.695 ± 0.047	1.519 ± 0.158	^c, ^f, ^g	0.791 ± 0.120	0.614 ± 0.055	1.425 ± 0.136	^b, ^f, ^g
PND 60
0 ppm	0.003 ± 0.000	0.004 ± 0.000	0.009 ± 0.001	^a, ^f, ^g	0.001 ± 0.000	0.003 ± 0.000	0.005 ± 0.001	^a, ^f, ^g
0.5 ppm	0.005 ± 0.001	0.010 ± 0.001	0.015 ± 0.002	^b, ^f, ^g	0.002 ± 0.000	0.006 ± 0.000	0.007 ± 0.001	^a, ^f, ^g
5 ppm	0.017 ± 0.004	0.083 ± 0.022	0.059 ± 0.013	^d, ^e	0.013 ± 0.002	0.040 ± 0.002	0.020 ± 0.002	^a, ^e, ^g
P (5ppm)	^h, ^j	^h, ^k	ⁱ, ^j		^h, ^j	^h, ^j	^h, ^j

Mean ± SEM; n ≥ 4

a–d, one-way ANOVA for tissues,

^a,

p< or = 0.0001;

^b,

p<0.001;

^c,

p<0.01;

^d,

p<0.05.

Post-hoc tests:

^e,

Blood × Brain; one-way ANOVA, Tukey’s HSD; p < 0.05,

^f,

Blood × Muscle; one-way ANOVA, Tukey’s HSD; p < 0.05

^g,

Brain × Muscle; one-way ANOVA, Tukey’s HSD; p < 0.05

h, I, one-way ANOVA for development time (5.0ppm dose),

^h,

p< or = 0.0001;

^i,

p<0.001

Post hoc:

^j,

PND6 × PND21; one-way ANOVA, Tukey’s HSD; p < 0.05,

^k,

PND21 × PND60; one-way ANOVA, Tukey’s HSD; p < 0.05