TABLE 2.
Escala Abreviada de Desarrollo, version 1a (EAD-1) screener results at 20–30 mo of age among children postnatally infected with ZIKVb (N = 60), Colombia, September-November 2017
| Developmental domains | Without adverse neurologic, eye, or hearing outcomes (N = 51) | With adverse neurologic, eye, or hearing outcomes (N = 9c) |
|---|---|---|
| Gross motor | (N = 51) | (N = 9) |
| Alertd | 0 (0%) | 1 (11.1%) |
| Fine motor | (N = 51) | (N = 9) |
| Alertd | 2 (3.9%) | 1 (11.1%) |
| Hearing and language | (N = 47e) | (N = 9) |
| Alertd | 6 (12.8%) | 2 (22.2%) |
| Personal-social | (N = 50e) | (N = 9) |
| Alertd | 3 (6.0%) | 1 (11.1%) |
The EAD-1 is a standardised, validated developmental screening tool in Colombia.
Participants were laboratory-confirmed with ZIKV infection by rRT-PCR within one week of symptom onset at 1–12 mo of age.
One child with hypotonia also had a diagnosis of Down syndrome; the other child with hypotonia also had a diagnosis of sensorineural hearing loss; three children had unknown hearing loss; and four children had an abnormal eye finding. The child with abnormal retinal scarring also had reported congenital toxoplasmosis.
An “alert” was based on cut points defined in the EAD-1 manual.
Children whose domain score could not be calculated due to incorrect EAD-1 application were excluded.