Skip to main content
. 2020 Dec 1;10:20915. doi: 10.1038/s41598-020-77345-y

Figure 1.

Figure 1

Pharmacokinetic study of ASP5878 and m-CNP in FVB/NJcl mice. (a) Plasma concentrations of ASP5878 after the subcutaneous administration of 300 and 1000 μg/kg ASP5878 into 23-day-old normal male mice. (b) Plasma concentrations of ASP5878 after the subcutaneous administration of 3 μg/kg ASP5878 into 22-day-old normal male and female mice. (c) Measurements of the lengths of the femur and tibia. Red lines indicate the distances measured to designate the lengths of the femur and tibia. (d) Plasma concentrations of m-CNP after the subcutaneous administration of 300 and 800 μg/kg m-CNP into 7-week-old normal male mice. Error bars denote the means ± s.d. (n = 3).