Table 2.
Distribution of concentration of urinary phthalate metabolites (ng/ml) in CANDLE and TIDES (n = 1481) and the National Health and Nutrition Examination Survey (NHANES).
| CANDLE and TIDES cohorts | NHANES | ||||||
|---|---|---|---|---|---|---|---|
| % < LOD | Geo. Mean(95% CI) | 50th | 75th | 95th | 2007–2008a | 2011–2012a | |
| MEP | 0 | 75.0 (68.9, 81.6) | 70.5 | 212.9 | 1330 | 88.2 (77.8, 99.9) | 37.7 (30.6, 46.4) |
| MBP | 1 | 11.8 (11.1, 12.4) | 12.7 | 23.1 | 55.5 | 19.3 (17.2, 22.0) | 7.1 (6.1, 8.4) |
| MiBP | 1 | 6.4 (6.1, 6.8) | 6.5 | 12.4 | 32.0 | 6.8 (6.2, 7.5) | 5.5 (4.9, 6.1) |
| MBzP | 3 | 6.8 (6.3, 7.3) | 7.7 | 17.3 | 57.1 | 6.7 (5.8, 7.8) | 4.3 (3.8, 4.8) |
| MCPP | 5 | 1.5 (1.4, 1.6) | 1.4 | 2.9 | 12.6 | 2.5 (2.3, 2.8) | 2.6 (2.2, 3.0) |
| MCOP | 0 | 4.1 (3.7, 4.4) | 3.4 | 10.9 | 67.9 | 6.5 (5.5, 7.7) | 17.1 (14.7, 19.9) |
| MCNP | 1 | 0.8 (0.7, 0.8) | 0.7 | 2.0 | 7.3 | 2.1 (1.8, 2.5) | 2.2 (2.0, 2.4) |
| ΣDEHPb | 0 | 0.09 (0.08, 0.09) | 0.09 | 0.16 | 0.55 | – | – |
| MEHP | 21 | 1.8 (1.7, 2.0) | 1.9 | 4.5 | 18.0 | 2.5 (2.2, 2.9) | 1.2 (1.1, 1.3) |
| MEHHP | 1 | 6.8 (6.4, 7.2) | 6.9 | 13.0 | 44.1 | 21.0 (17.8, 24.8) | 7.2 (6.8, 7.7) |
| MEOHP | 0 | 5.4 (5.1, 5.7) | 5.2 | 9.8 | 33.2 | 11.8 (10.0, 14.0) | 4.7 (4.4, 5.1) |
| MECPP | 0 | 11.1 (10.5, 11.7) | 10.8 | 19.7 | 68.4 | 32.3 (27.8, 37.5) | 11.8 (10.8, 12.9) |
Concentrations in table are not adjusted for specific gravity.
a
Geometric mean in women as reported by Centers of Disease Control and Prevention (Centers for Disease Control and Prevention 2019)
b
ΣDEHP = umol/L, (MEHP*(1/278.34)) + (MEHHP*(1/294.34)) + (MEOHP*(1/292.33)) + (MECPP*(1/308.33))