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. 2020 Aug 18;9(4):739–756. doi: 10.1007/s40123-020-00291-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 4 — Serial SD-OCT scans of a 68-year-old woman with soft drusen and an adjacent hypo-reflective space who was followed up for 3 years. OCT scans were taken on yearly intervals. Note the gradual coalescence of soft drusen and the development of a drusenoid PED. The PED has a homogenous, mildly hyper-reflective interior, and Bruch’s membrane is seen at its base. During the observation period the hypo-reflective space and visual acuity remained stable