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. 2020 Dec 1;10:20902. doi: 10.1038/s41598-020-78074-y

Table 2.

Prognostic factors evaluated by log-rank test survival analysis.

Characteristics Number Median OS (months) Log-rank test Univariate
p value p value
Sex 0.625 0.765
Male 35 18
Female 27 17
Age (years) 0.752 0.654
 ≤ 50 30 20
 > 50 32 19
Tumor location 0.156 0.235
Upper 26 15
Middle 28 17
Lower 8 19
Initial length 0.023 0.164
 ≤ 5 cm 35 21
 > 5 cm 27 16
Pathological grade 0.102 0.274
I 12 20
II 39 18
III 11 15
Initial clinical stage 0.412 0.657
II 26 20
III 36 17
Initial ECOG-PS 0.758 0.458
0–1 39 19
2 23 18
3 0
Initial radiation dose 0.532 0.178
 ≥ 60 Gy 57 19
 < 60 Gy 5 18
RFS 0.001 0.001
 ≥ 12 month 39 26
 < 12 month 23 13.5
Group 0.352 0.473
NBT+EBRT 31 19
EBRT 31 18

EBRT external beam radiotherapy, ECOG-PS Eastern Cooperative Oncology Group performance status, NBT neutron intraluminal brachytherapy, RFS recurrence-free survival.