Table 2.
Risk factor analysis of acute kidney injury in patients with acute decompensated heart failure.
| Variables |
Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Age | 1.003 | 0.989–1.018 | 0.661 | – | – | – |
| Sex | 0.631 | 0.345–1.157 | 0.137 | – | – | – |
| Diabetes history | 1.506 | 0.814–2.784 | 0.192 | – | – | – |
| Myocardial infarction history | 1.849 | 0.778–4.392 | 0.164 | – | – | – |
| Heart failure history | 0.444 | 0.183–1.080 | 0.063 | – | – | – |
| Coronary heart disease | 0.552 | 0.254–1.125 | 0.069 | – | – | – |
| Hypertension | 1.464 | 0.637–3.368 | 0.370 | – | – | – |
| Cardiomyopathy | 2.121 | 0.912–3.125 | 0.413 | – | – | – |
| LVEF | 1.192 | 0.600–2.370 | 0.616 | – | – | – |
| NT-pro-BNP | 1.213 | 0.824–2.859 | 0.123 | – | – | – |
| Serum albumin | 2.052 | 1.032–3.854 | 0.045 | 1.245 | 0.625–2.589 | 0.489 |
| Scr | 2.125 | 1.098–3.945 | 0.038 | 1.056 | 1.029–1.165 | 0.047 |
| eGFR | 1.899 | 1.021–3.588 | 0.048 | 1.789 | 0.785–4.268 | 0.175 |
| sNGAL | 1.525 | 0.789–2.975 | 0.110 | – | – | – |
| uNGAL | 1.956 | 1.125–4.129 | 0.026 | 1.698 | 1.084–2.964 | 0.038 |
| smiR-652-3p | 1.912 | 1.112–3.986 | 0.029 | 1.519 | 1.051–2.881 | 0.042 |
| umiR-652-3p | 2.135 | 1.369–4.398 | 0.006 | 1.945 | 1.569–4.010 | 0.015 |
OR, odds ratio; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-pro-BNP, N-terminal pro-brain natriuretic peptide; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; sNGAL, serum neutrophil gelatinase-associated lipocalin; uNGAL, urinary neutrophil gelatinase-associated lipocalin; smiR-652-3p, serum microRNA-652-3p; umiR-652-3p, urinary microRNA-652-3p.