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. 2020 Nov 23;7:1571–1577. doi: 10.1016/j.toxrep.2020.11.008

Table 2.

Protective effects of various treatments against GO-induced ROS formation in rat renal cells.

Treatment ROS formation (fluorescence intensity)
15 min 30 min 60 min
Control isolated renal cells 47 ± 3 55 ± 2 62 ± 4
+GO (5 mM) 62 ± 5a 75 ± 3a 95 ± 4a
 +Resveratrol (50 μM) 57 ± 3 62 ± 4b 71 ± 3b
 +Curcumin (5 μM) 54 ± 5 56 ± 3b 67 ± 5b
 +Gallic acid (10 μM) 51 ± 3b 56 ± 5b 73 ± 3b
 +DMSO (150 mM) 50 ± 5b 61 ± 3b 75 ± 6b
 +Mannitol (50 mM) 48 ± 4b 63 ± 4b 76 ± 4b
 +Carnitine (2 mM) 42 ± 3b 59 ± 2b 72 ± 5b
 +L-Glutamine (1 mM) 49 ± 3b 67 ± 3b 78 ± 5b
 +Chloroquine (100 mM) 54 ± 4 64 ± 5b 81 ± 3b

Data are expressed as mean ± SD of three separate experiments (n = 3).

a

Significantly different from the control renal cells (P < 0.05).

b

Significantly different from the GO-treated renal cells (P < 0.05). GO: glyoxal; ROS: reactive oxygen species; DMSO: dimethyl sulfoxide and SD: standard deviation.