Table 2.

Summary of inclusion and exclusion criteria.

Inclusion Criteria	Exclusion Criteria
Patients exhibited sufficiently high neuroticism score based on the NEO FFI (at least one standard deviation above a point estimate of the general adult population mean*)	History of exclusionary neurological or cognitive disorder(s)/event(s), psychiatric conditions, or mood disorders, including schizophrenia and bipolar I
Controls did not meet DSM-5 criteria (currently or historically) for the diagnosis of any psychiatric or cognitive disorder and exhibited sufficiently low neuroticism based on the NEO FFI (at least one standard deviation below a point estimate of the general adult population mean*)	Current substance use disorder (as defined by the DSM-5), including addiction to alcohol, recreational drugs (e.g. cocaine, heroin, and methamphetamines), or prescription medication
Age 18–60	MRI contraindication
Fluent in English (written and oral)	HIV positive
	Active Hepatitis B or Hepatitis C
	Female participant was pregnant, breastfeeding, or trying to become pregnant

^*Mean NEO-FFI neuroticism scores were determined from separate distributions for males (mean = 19.1, sd = 7.1) and females (mean = 22.2, sd = 7.9) based on previously collected data from a sample of 635 adults (McCrae et al., 2007).