Fig. 3.

Independent component analysis. Increased resting-state functional connectivity in ALS patients after six months accounting for changes at the ALS Functional Rating Scale Revised (ALSFRS-R), time between scans and voxel-based grey matter density. Results are overlaid on the Montreal Neurological Institute (MNI) standard brain in neurological convention and displayed at p < 0.05 Family-wise error corrected for multiple comparisons. X values denote x-MNI coordinates. Colour bar represents p values.