Table 5.
Intrinsic network functional connectivity multiple regression analysis.
Network | Group | Contrast | Measure | Correlation | Brain Region | Cluster Size | MNI Coordinate |
t Stat. | Z score | p FWE Peak | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|
x | y | z | ||||||||||
SN | Experimental | Post NFB | CAPS Decrease | Negative | Supplementary Motor Cortex | 13 | 4 | 12 | 58 | 6.09 | 4.32 | 0.040 |
Anterior DMN | Experimental | Post > Pre NFB | EEG-Training Alpha Dynamic | Negative | Right Posterior Insula* | 12 | 40 | −6 | 6 | 4.68 | 3.66 | 0.015 |
Pre- and post-neurofeedback intervention correlations for the PTSD experimental group and sham-control group (voxel-wise pFWE < 0.05, k = 10). * Denotes region-of-interest analysis also evaluated at the same error protection rate. Acronyms: DMN = default mode network, SN = salience network, CAPS = clinician administered PTSD scale (PTSD severity), NFB = neurofeedback.