Table 1.
Patient’s characteristics.
| Total (n = 28) | First line (n = 6) | Second or later line (n = 22) | p value | |
|---|---|---|---|---|
| Median age, years (range) | 67 (20–82) | 76 (58–82) | 62 (20–76) | 0.013 |
| Sex, n (%) | 0.16 | |||
| Male | 14 (50) | 5 (83) | 9 (32) | |
| Female | 14 (50) | 1 (17) | 13(68) | |
| ECOG PS, n (%) | 0.40 | |||
| 0 | 2 (7) | 1 (17) | 1 (5) | |
| 1 | 13 (46) | 2 (33) | 11 (50) | |
| 2 | 11 (39) | 2 (33) | 9 (41) | |
| 3 | 2 (7) | 1 (17) | 1 (5) | |
| Histology, n (%) | 0.72 | |||
| Dedifferentiated liposarcoma | 10 | 2 (33) | 8 (29) | |
| Leiomyosacroma | 6 | 2 (33) | 4 (14) | |
| Others | 12 | 2 (33) | 10 (38) | |
| Previous chemotherapy, n (%) | ||||
| 0 | 6 (21) | 6 (100) | 0 | |
| 1 | 9 (32) | 0 | 9 (41) | |
| > 1 | 13 (47) | 0 | 13 (59) | |
| The reason for avoiding doxorubicin | ||||
| Cardiac comorbidities | 4 (14) | 4 | 0 | |
| Old age | 2 (7) | 2 | 0 | |
ECOG PS Eastern Cooperative Oncology Group Performance Status.