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. 2020 Dec 1;6:35. doi: 10.1038/s41526-020-00125-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a MSCs were subjected to LIV_AT and stained with DAPI (blue) and YAP (red). Confocal images indicated increased nuclear YAP levels following acute LIV_AT applied as five 20 min vibration periods separated by 1 h. b Quantitative analysis of confocal images showed a 32% increase of nuclear YAP in LIV_AT samples compared to controls. n > 400/grp, group comparison was made a Mann–Whitney U-test, ****p < 0.0001. Error bars represent standard deviation. Scale bar: 10 μm. Full statistical details were provided in Supplementary Table 4.