Table 3.

Loci for autosomal recessive HL in 13 Pakistani families.

Family ID	Chromosomal Band	Region of Autozygosity Identified by Linkage Analysis (hg19)	Length (Mb)	LOD	Causal Gene in Locus	Gene Coordinates (hg19)
Family 1	11p12-q13.4	39,536,493–73,025,971	33.5	2.529	FGF3	chr11:69,624,736–69,634,192
Family 2	11q13.1-q13.3	63,870,810–69,964,525	6.1	3.73	FGF3	chr11:69,624,736–69,634,192
Family 3 *	13q12.11-q14.11	22,661,666–41,063,028	18.4	1.927
Family 4	11q13.3-q14.3	69,063,393–88,489,081	19.4	2.529	MYO7A	chr11:76,839,310–76,926,284
Family 5	11q13.5-q14.1	76,792,431–80,457,784	3.7	1.927	MYO7A	chr11:76,839,310–76,926,284
Family 6	1p22.2-p21.2	88,430,037–102,069,696	13.6	1.927	CDC14A	chr1:100,810,598–100,985,833
Family 7	13q22.1-q31.3	74,995,660–90,925,494	15.9	1.2	SLITRK6	chr13:86,366,925–86,373,554
Family 8	No interval close to MYO7A
Family 9	10q21.2-q22.3	64,059,261–78,005,230	13.9	3.006	CDH23	chr10:73,156,691–73,575,702
Family 10	13q11-q12.11	19,121,950–22,395,049	3.3	2.529	GJB2	chr13:20,761,609–20,767,037
Family 11	13q11-q12.12	19,121,950–23,534,670	4.4	2.529	GJB2	chr13:20,761,609–20,767,037
Family 12	17p12-p11.2	13,801,016–21,539,613	7.7	2.529	MYO15A	chr17:18,012,020–18,083,116
Family 13	10q21.2-q23.31	61,998,060–91,002,927	29.0	1.2	CDH23	chr10:73,156,691–73,575,702

Abbreviations: LOD, logarithm of the odds. * Family 3 revealed a homozygous interval outside but near the GJB2 gene locus.