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. 2020 Oct 10;9(4):52. doi: 10.3390/antib9040052

Figure 4.

Figure 4

Comparison of human PF4 (hPF4) and mouse PF4 (mPF4) sequences, showing the overlap of KKO and RTO epitopes. Since KKO preferentially binds to PF4 tetramer, its epitopes are contributed by amino acid residues from different chains within a PF4 tetramer. Dash lines depict the internal disulfide bonds.