Table 3.
Postsynaptic effects of general anesthetics on receptors.
| Volatile Anesthetics | Intravenous General Anesthetics | ||||||
|---|---|---|---|---|---|---|---|
| Halothane | Enflurane | Isoflurane | Propofol | Etomidate | Ketamine | Thiopental | |
| GABAA | + [102, 287] | + [102, 233, 287] | + [102, 287] | + [229, 231, 287] | + [287, 288] | + [225, 287, 289] | |
| α1β2γ | + [225] | ||||||
| α5β2γ2s | + [225] | ||||||
| α6β2γ2s | + [225] | ||||||
| α-subunit | + [244, 290] | + [230-232] | |||||
| β-subunit | + [225] | + [230-232] | + [240-242] | + [225, 289] | |||
| γ-subunit | + [291] | ||||||
| NMDA glutamate | - [256] | - [255] | - [292] | ||||
| AMPA glutamate | -[263] | ||||||
| Glycine | + [293] | + [275] | + [266] | ||||
| N-Ach (neuronal receptor) | - [284] | - [284] | - [276] | ||||
“+”: Potentiation; “-”: inhibitory effect.